PDF The Toxic Induction of Irritant Asthma, Irritant Rhinitis, í multi channel.co

Untoward reactions to environmental chemicals particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving than one organ system have been poorly understood and an area of great controversy Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists Recognition that rhinitis while sometimes regarded as a trivial disease is associated with extra airway manifestations such as fatigue and disturbances of sleep mood and cognition further elucidates how chemical exposures can be serious for susceptible individualsThis book reviews current scientific understanding of irritant airway inflammation and related conditions including cardiovascular effects of particulate exposures airborne contact dermatitis and irritant dermatitis and the brain as a target organ for both allergic and irritant reactions It is essential reading for physicians and other healthcare workers caring for patients with environmental intolerances Allergists toxicologists occupational and environmental physicians and pulmonologists will find the materials particularly valuable Patients and advocates for those with chemical intolerances will also find the book of interest

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